Wow, a very general question without alot of background.
Will you/your spouse need to work and what is your line of work?
Do you have children that need access to good schools?
Do you have health issues (or family history) that necessitates being
near a good medical center/hospital?
Do you need to be near adult education resources in order to further
education or change careers?
Are you self-sufficient and wish to live in a rural environment or do
you need an urban environment?
I would suggest you review your family’s needs first, then look at all
the Money magazine and U.S. News & World Report “Best Places to Live”
surveys to learn a bit more about the most recommended places. Those
surveys will give you a better idea of all the considerations in such
a question.